Dear Dharnesh Chandra Sharma,

The underying reason WAS that hemolysis rates below 0.8% at the end of storage time would result in an acceptable in vivo recovery 24 hours after transfusion.

Kind regards,

Andreas

Dear Andreas 

Thanks for responding the question.AS I am also searching it on google, there is also a some relationship between  the survival  percentage of transfused RBCs  after 24 hours and expiry date of the unit . 

regards 

Hi Dharmesh and Andreas, our company has as product HemSolTm that can preserve RBC's and platelet functions well beyond their expiration dates using conventional storage solutions.

Unfortunately, we are a small company that have had problems with funding our research. The FDA accepted a phase-1 clinical trial with Inova hospitals. We have done small animal trials and in vitro trials (attached), but the FDA wanted rabbit trials before they would sign off on human trials.

The rabbit trials they wanted done will cost ~$400,000, but we do not have the capital to do this.   

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  Dear  Stefansson 

 Thanks for providing me the valuable feed  .