Can a drug affect both the protein synthesis as well as degradation of misfolded proteins?

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What is the maximum value of Divesity Gian in MIMO? For two antenna system its 10dB. As no. of antennna increse diversity gain increase or decrease?

Somewhere on the internet, it's reported the maximum diversity gain limit theoretically can be achieved is 10dB. Some papers said it increases with more antennae and some said it will decrease.

09 June 2024 5,121 2 View

Fully funded phd ?

any fully funded phd position in wildlife ?

25 May 2024 7,976 2 View

Access to document containing CPCB calibration curve and uncertainty for PM2.5, SO2, O3, and NO2 monitors?

I am wondering if anyone has come across calibration curve and uncertainty for PM2.5, SO2, O3, and NO2 monitors maintained and operated by the CPCB? Please share link herein for the same if you...

25 April 2024 7,164 5 View

How to model or program a cascade refrigeration system using natural refrigerants on MATLAB ?

What are different ways of modelling and simulation of cascade refrigeration cycleusing natural refrigerants on MATLAB without using simscape ? How to write program for it and connect MATLAB...

02 April 2024 487 2 View

Classical text is important or research journals are important?

because people are citing/talking less about Classical texts discovered by Rishi/sages. Rishi has the broad scientific knowledge as per their practical and theoretical practices.

30 March 2024 2,013 0 View

How to interpret the LCMS data with using peak values?

How to evaluate the compounds with usage of peaks and their respective values in LCMS - TOF instrumentation? Is there any web portals for the data interpretation? I Have got Both LC (2 Files) MS...

13 March 2024 7,940 1 View

Understanding factors leading shift from spiritual-cultural drinking to modern alcohol consupmtion in Warli tribe?

Alcohol consumption shift. Socio-econo-cultural factors, globalisation, westernisation, religious conversion role in alcohol consumption shift

12 September 2023 4,757 0 View

How fin and fan design is done for for thermoelectric refrigeration system ?

I have not understood here the method of design of fin and Fan for thermoelectric refrigeration system in paper attached .....................

09 August 2023 8,355 0 View

What best method to obtain correct composition of Al2024 series ? OES or EPMA?Steps?

I have tried OES method to obtain composition of 2024 T4 multiple times. As per standard composition Cu should vary between 3.8-4.9 and Mg should vary between 1.2-1.9. The problem coming is that...

18 July 2023 450 0 View

Are D16AT and 2024-T4 same ??

In all research paper i found the Aluminium alloy D16AT and 2024T4 having same chemical composition . They are subjected to same heat treatment process. Are they different or same ???

16 July 2023 8,039 4 View

Why does my protein refolded to beta sheet during thermal denaturation analysis?

Hi! So i attempted to understand a novel protein behavior towards heat application by analyzing its secondary structure change. I subjected the protein to a thermal denaturation analysis using...

06 August 2024 1,989 3 View

Why my colony PCR results of my recombinant bacterial not showing any results?

I am performing ligation of the plasmid and a target gene. The steps I have taken are: 1. Double digestion of the plasmid and target gene 2. Ligation of the plasmid with the target gene 3....

05 August 2024 2,570 3 View

For an in-vitro drug release study, what molecular weight cut-off (MWCO) dialysis bag is required for a 117 kDa protein?

kindly reply me. Thanking you in advance.

05 August 2024 7,727 4 View

The Optimal Experimental Approach for Gene Function Analysis?

What is the most suitable experimental setting to understand the consequences of a particular gene: (1) targeted degradation of the specific transcription factor (TF) of the gene, followed by...

04 August 2024 6,265 1 View

Transfection in HEK293T cells?

Dear All, I am trying to transfect a pCDNA3.1 vector containing my gene of interest. The purpose is to figure out the localization of the protein of interest. I have fused the protein with GFP on...

31 July 2024 9,892 4 View

Inquiry on Maximum Nucleic Acid Volume for 2.5 mL Liposome Solution?

I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...

30 July 2024 6,420 1 View

How to retain the a GFP tagged gene expression in stable cell line?

Hello , I established a stable cell line expressing GFP tagged to a centrosomal gene having G418 drug selection marker. I validated the stable line by IFA and Western blotting, results are fine....

29 July 2024 5,007 0 View

What is the relationship between protein structure and N or C terminal tagging choosing?

I want to do 2,3-butanediol dehydrogenase(BDH) enzyme purification to confirm its activity for 2,3-butanediol. Before that, I need to confirm which N or C terminal tagging is better for enzyme...

28 July 2024 366 3 View

Why cannot i find my protein on cell surface after antibiotic selection of expressing plasmid?

I cannot confirm cell surface protein expression by flow cytometry even after transfection and antibiotic selection of cells. Does it take long for proteins to express on the cell surface? the...

28 July 2024 3,178 3 View

EDC carbodiimide and NHS easter 's half life among different pH?

It has been long known that EDC carbodiimide and NHS easter's half life agains hydrolysis are highly related to pH. However, very surprisingly, not yet found a paper giving a table/chart of their...

25 July 2024 8,738 0 View