Bruker's LCMS EVO TQ vitamin D2 BLANKS contamination. Any experts here fimiliar with the application?

13 August 2023 1 10K Report

Hi people, any body working with Bruker's LCMS EVO TQ here? We are facing an issue with vit. D2 in serum and blood. Blanks and Cal 0 showing peaks for vit. D2 while QC for vit D2 is fine. And no issues with vitamin D3 blanks and Cal 0 at all. Only D2 showing contamination. We recently changed extraction column and every thing was OK for few days and now this problem started. Any suggestions would be highly appreciated. Thank you 🙏

Muhammad Hameed

Can any body reply please. Any expert opinion?

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