I am looking for a comprehensive pathway to pass from a kegg network file (KGML) to a boolean interactive network. There are a lot of differents softwares and applications to do so available but due to my inexperience I don't find an adequeate one to fill the gap between that two differents outputs. I have been looking to GENEsim, CellDesigner with BiNom app on Cytoscape and more but it's not good.

I know this proccess could be a tricky one but any suggestion of a software that would help to "prune the graph" in an automatic way or through automatic suggestions v(based on highly connected nodes, hubs identification an/or stable states of the network interaction or so) would be really appreciated.

Thank you,

Juan