Is there enough ROS formed inside cell for cidal activity ?

Increasing number of reports says that after the exposure of bacteria to bactericidal agents, there is formation of reactive oxygen species. My specific quaestion lies in the quantity of ROS, if...

01 February 2019 2,164 6 View

Can P-gp inhibitor be used to enhance the rifampicin bio-availability ?

07 August 2017 1,545 3 View

How to interpret the log cfu below detection limit ?

If one is spotting the 20 microlitre spots directly and dilutions from total 1 ml of unknown CFU sample. If one gets one or two colonies on two plate and no colonies on plate on other four plates....

31 December 2016 1,594 9 View

Why cytotoxicity for antimicrobial compounds is assessed on HepG2/J774 cell lines knowing the fact originated from cancer cells ?

Dear researchers I wish to knew the reason why researchers use cancer cell lines for assessing the cytotoxicity. Do they mimic the normal cells of human ? If yes then how ?

11 December 2016 7,569 5 View

Is there any software to make figures for membrane transport through transport proteins like efflux/influx of drugs ?

Dear Researchers I have came across some softwares which are helpful in drawing the immunological pathways, metabolic pathways but I cant find the software which can be helpful to draw the simple...

09 October 2016 9,862 0 View

First template cDNA buffer is missing, can make manually ?

07 August 2016 6,363 1 View

How to see cDNA first template on gel ?

Can we see whether cDNA is formed, particularly on gel. We measure the cDNA by 260/280 absorbance ratio and RNA is seen on gel. But could we see the freshly prepared cDNA first template on gel....

07 August 2016 880 6 View

Can a biologist think of pure demarcation between vegetarian or non vegetarian ?

Is there a pure line demarcation between vegetarian and non-vegetarian ? If somebody talks of purely vegetarian, is he not eating yeast, bacteria, molds? Need only scientific input.

31 December 2015 2,127 2 View

Alkaline pH biosensor

I want to study some compounds which raises the pH to alkaline for their bactericidal action. Is there any biosensor available, or well known method to measure alkaline pH in bacteria.

01 January 1970 3,323 7 View

Could you recommend any books about Number Theory?

Beginner level books. High level books. Analytical Number Theory. Algebraic Number Theory. Combinatorical Number Theory. Books about partitions. Books about primes.

03 March 2021 7,174 5 View

What kind of intervention will be relevant to increase motivation among young sport trainees?

Any suggestion on what book to read is also welcome.

03 March 2021 1,646 4 View

Does the pressure(-600 mmHg) affects pH?

When I conducted the degassing experiment using decompression under anaerobic condition(and I used ferrous based chelating agent), the oxidized ferric were observerd. So, could you tell me the...

03 March 2021 4,892 5 View

Resistor definition in Piezoelectric bimorph with ANSYS workbench

Hello, good day! I am trying to simulate similar bimorph piezoelectric harvester with below commands. However, the output power doesn't change with resistor value. Please help to find the reason. ET,10,CIRCU94,0 !SET UP RESISTOR R,1,100000 !RESISTANCE VALUE TYPE,10 !SET ELEMENT TYPE E,1,2 !CREATE RESISTOR BETWEEN NODES 1 AND 2 Thanks in advance Regards,

02 March 2021 0 0 View

How the parameters (such as Mw, Chemical bonds, polymer bland and so on) affect the mechanic property of polymer (such as storage, loss modulus) ?

Anyone can recommend any books on such topics? Thanks in advance.

02 March 2021 8,457 2 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

What analysis to choose with a large neste dataset and clearly skewed or kurtotic distributions?

Hello! I have a dataset of n=3000 nested within 8 countries with approximately 200 or 400 responses in each country. I originally planned to perform multilevel modelling with 4 dependent variables...

02 March 2021 6,865 1 View

I am interested in medicinal chemistry field, which books are highly recommended to learn from?

I am at the beginner level in drug design and drug discovery, and I am interested to learn more about this field. Which books are highly recommended to start from and gives me all essential...

02 March 2021 8,437 2 View

Please suggest a good text book for "Research Methodology in Life Sciences". Which book would be good for PhD Scholars?

Please provide Book Title and author name

02 March 2021 9,059 3 View

Which is a lucid standard comprehensive book to guide on psychological scale construction and its standardization?

02 March 2021 7,082 3 View