There are so many disciplines involved in drug discovery that I doubt you will be able to find every aspect covered in any level of detail in a single book.

This may lead you in the right direction:

http://onlinelibrary.wiley.com/doi/10.1002/0471141755.ph13a01s31/abstract

Hi

I hope that the following book will help you.

Frontiers in Anti-Infective Drug Discovery

Volume 3

by

Atta-ur-Rahman , M. Iqbal Choudhary

http://ebooks.benthamscience.com/book/9781608059126/

Recent Patents on Anti-Infective Drug Discovery

http://benthamscience.com/journals/recent-patents-on-anti-infective-drug-discovery/author-guidelines/

Dear Samsher Singh

Check the fallowing link for general study.

https://www.amazon.com/Drug-like-Properties-Concepts-Structure-Optimization/dp/0123695201

A lot of topics relevant to anti-infective drug discovery (and drug discovery in general), not limited to enzymology, are covered in this book by Robert A. Copeland:

EVALUATION OF ENZYME INHIBITORS IN DRUG DISCOVERY

A Guide for Medicinal Chemists and Pharmacologists, 2nd edition

The table of contents can be seen here:

http://samples.sainsburysebooks.co.uk/9781118540404_sample_413714.pdf