Please advise any good startup companies which mainly based on benzimidazole derivatives drug development, better at late stage of pre-clinical or Pre-IND stage. Thanks
Hi all, I have a ex vivo drug screening system for leukaemia, but I realised some samples contains both leukaemia and a significant amount of healthy cells (5-30%). I am looking for a no-wash (or...
04 June 2024 3,779 0 View
Hi everyone, I've been having difficulty in purifying a protein. It is a beta barrel, integral membrane protein. My protein is expressed and purified recombinantly. My target protein is running...
30 May 2024 7,604 3 View
I'm interested in models of CPD that take into account both of these key criteria.
19 March 2024 4,482 1 View
Hi all, I am currently helping my colleague to do a drug screening assay. We have use dTag to "turn off" the protein expression of our protein of interest and treat the cell line with drugs...
11 January 2024 8,422 2 View
Hi all, I have been doing drug screening on clinical samples and multiple 384-well plates are used for each samples. However, when we look at the cell number in the DMSO control on each plate,...
05 December 2023 4,478 7 View
Specifically, I am wondering if I can predict the surface marker expression of CD14 and CD16 on monocytes based on scRNAseq data that includes the expression level of those two genes. Does anyone...
29 March 2023 6,818 3 View
Hi Community, I am planning to express 6 human proteins in a mouse cell line. They are from 400 to 800 bp long. I want to use three vectors, each containing two CDS connecting with 2A peptides,...
04 February 2023 3,165 1 View
Hi Fellow Researcher, I understand the title isn't clear enough. Allow me to explain. I have two pairs of cell lines (pair 1: cell line A, cell line A with WT gene 1; pair 2: cell line A, cell...
11 January 2023 7,213 1 View
Looking for any freeware on potential drug candidates screening. Any advice please.
01 January 2023 910 0 View
There seems to be much previous interest in developing haemodynamic monitoring equipement, espcially non-invasive ones, for haemodialysis. However, there is not much over the last decade. Can...
21 December 2022 1,359 2 View
I want to explore the long-term effects of incarceration on a youth's developing brain. I also want to explore research that looks critically at incarceration and punitive measures as the primary...
12 August 2024 862 0 View
kindly reply me. Thanking you in advance.
05 August 2024 7,727 4 View
Please go through my Abstract. I can also share a proposed Thesis Outline.
04 August 2024 2,077 0 View
or we can collaborate
01 August 2024 6,705 2 View
What are the roles of innovation in achieving the Sustainable Development Goals (SDG)?
31 July 2024 3,533 2 View
We are looking for projects for a team of professional developers About us We are a team of experienced developers with over 10 years of experience in various programming fields. Our mission is to...
30 July 2024 8,377 0 View
I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...
30 July 2024 6,420 1 View
Your comments
28 July 2024 2,822 2 View
need of sensor details or sensor development for this question.
28 July 2024 4,539 3 View
Understand how to utilize biosynthesis to develop natural and sustainable solutions to address heavy metal pollution and improve environmental and agricultural conditions.
26 July 2024 1,469 1 View