In general, are the type strains of human pathogens are pathogenic? e.g. Klebsiella pneumonia, Staphylococcus aureus,
Pseudomonas aeruginosa, etc.
All of your examples are opportunistic bacteria no pathogenic but yes type strain can be pathogen for pathogenic bacteria.
The named species are facultative pathogenic, i.e. they are virulent and can cause infection, although certain host factors are required (immune suppression, breakdown of barrier functions, etc.). “Type strain” says nothing about the ability of that particular isolate to cause infections. But if you go to the description of a type species you usually find information about the origin of that particular strain (whether it comes from an infection or not). Staphylococcus aureus subs. anaerobicus ATCC 35844, for instance, has been isolated of an “abscess of young sheep” (http://bacdive.dsmz.de/index.php?search=dsm%2020714).
In general, when working in a lab with highly enriched number of bacteria, be extremely cautious and handle your cultures as being infectious agents!
Of course they are pathogenic; virulence is however a function of how they have evolved through various degrees of exposures.
You can check the pathogenicity of any strain either phenotypically or genotypically by molecular detection of their virulence genes.
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