considering that Wilson's disease prevalence is very low, and the neurological component even lower than the liver, what other therapies could be considered with a patient who presents a dystonic chorea and moderate cognitive commitment, who has not responded to handling with zinc, penicillamine nor triantene hydrochloride?
Neurology. 2012 Aug 7; 79(6): 597–603. doi: 10.1212/WNL.0b013e318263c443PMCID: PMC3413759PMID: 22815556
Evidence-based guideline: Pharmacologic treatment of chorea in Huntington disease
Report of the Guideline Development Subcommittee of the American Academy of NeurologyMelissa J. Armstrong, MD, MSc and Janis M. Miyasaki, MD, MEd, FAAN
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https://www.mayoclinic.org/diseases-conditions/wilsons-disease/diagnosis-treatment/drc-20353256
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