I appreciate if you could numerate some examples of intrinsically fluorescent tyrosine kinase inhibitor ?drug
Staurosporine is fluorescent (excitation about 290 nm, emission about 390 nm).
Thank you for your prompt answer. I checked some selling pharmaceutical companies, but no excitation and emission wavelengths are listed. How to confirm ?? also, are there any other examples ??
Here is a reference for a staurosporine fluorescence-based binding measurement:
http://www.ncbi.nlm.nih.gov/pubmed/18047825
Thank you. Do u know other native fluorescent compounds that inhibit tyrosine kinase.
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