Most lipases act at a specific position on the glycerol backbone of a lipid substrate. For example, HPL often converts triglyceride substrates into monoglycerides and two fatty acids. I do not think lipases are able to degrade mycolic acids, which are long-chain fatty acids.

But, it is good to try screening of  lipases from nature  for degradation of mycolic acids. You can use mycolic acids as a sole substrate for enrichment of lipase producers from soil or other samples available in nature.