Given that there are differences in cortisol production regarding gender (women produce more), would this also equate to differing ratios regarding catecholamines as well? Could this be an explanation why women, on the average, have lower tolerance to orthostatic stressors? Or rather, regardless of gender, would orthostatic instability come about because of lower concentrations of catecholamine release from the adrenal glands and/or post ganglionic sympathetic nerve endings?
Do not quote me on this, but I vaguely recall women may tend to get takotsubo (broken heart) syndrome more often than men. Takotsubo is characterized by an apical ballooning of the heart that is caused by a surge in catecholamines.
As far as I remember there are gender differences regarding serotonin and noradrenalin /release in male and female wistar rats. Please see in Spinal cord noradrenergic dynamics in diabetic and hypercortisolaemic states
MS Bitar, KT Bajic, T Farook, MI Thomas, CWT Pilcher
Brain research 830 (1), 1-9
Alex: takotsubo is more prevalent in women than in men, which is due to a massive catecholine release. It would be interesting to know the actual concentration of catecholamines needed to bring about takotsubo.
Katarina: thanks for the article!
Pas de qois, you welcome! If there is no specific, data there in the paper, I am sure I have it raw, somewhere, but it need a lot of "digging" and nowadays we have urgent things to do here in flooded Serbia.
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