What are typical Cu sources causing Cu adducts in ESI MS?

Hi everybody, currently I observe quite frequently Cu-adducts on my ESI high resolution MS, especially when analyzing ligands. There was no Cu used for the synthesis, so it must come from the...

21 October 2020 5,630 5 View

Which is the Risk of Long QT and Sudden Cardiac Death by Drugs Used to treat COVID-19?

Numerous drugs are used these days without in-depth evaluation of efficacy and safety for the treatment of life-threatening complications of COVID-19. Among these, an important number are known...

26 March 2020 816 17 View

Which pharmacological modulation of immune response to SARS COV-2 could reduce the incidence of acute respiratory distress syndrome?

Differences in immune responses to emerging corona viruses and the difficulties of developping vaccines contribute to a surge in ARDS in vulnerable populations, leading to acute shortages and...

16 March 2020 3,520 26 View

Does anyone know a freeware tool that can align exon and intron sequences to a template DNA sequence?

I am seaqrching for a tool that can align exon and intron sequences to a template DNA sequence without disrupting any of the short sequences. I remember that DNAStar was able to do this. Does...

12 December 2019 8,902 3 View

Does anyone have any early World History LGBT secondary sources that are non-western?

I am looking to integrate unheard voices into the survey class, before 1500. If you have secondary sources that you are willing to share please let me know.

22 October 2019 1,233 4 View

Taxonomy of Data Sources?

Can anyone suggest a reference that deals with a decent, contemporary taxonomy of data sources? There is the old taxonomy by Cattell: Q-Data (= Questionnaire Data), T-Data (= Test-Data), and...

22 October 2019 8,429 1 View

Why is the monoisotopic peak sometimes slightly different to the calculated m/z?

Hi, I just had a look on a recent analysis (on C26H19F4N2O4Se+) and was wondering why the simulated monoisotopic peak of the molecular ion (579.0441) is slightly differnt to the calculated m/z...

26 March 2019 7,774 12 View

Which staining method to use to quantify low level nerv damage?

02 April 2017 4,332 3 View

Does anyone have a transfection protocol for the NSCLC cell line PC9?

I use HiPerFect from Quiagen. I transfect microRNAs which lead to a reduction of their targets in other cell lines like HCC4011, HCC827 and A549 and siGLO as a control. But I can't detect...

17 February 2017 3,919 3 View

I have a result that generated additional hypotheses, can I include the additional hypotheses and results in the same paper?

Our unpublished results have generated several additional hypotheses. I'd like to keep both the original research goals and the generated hypotheses in the same paper. I was thinking of splitting...

31 December 2016 5,389 24 View

How to manually calculate p value in ANOVA? what is the equation or formula for it?

How to manually calculate p value in ANOVA? what is the equation or formula for it?

03 March 2021 4,928 5 View

Can we distinguish the type of free fluid inside the pelvic and abdominal cavities whether blood or serous fluid using the ultrasound?

during ultrasound examination of acute abdomen, sometimes we see free fluid , can we know the type of fluid ,whether blood or not , using ultrasound only? if yes , what are the sonographic...

01 March 2021 7,476 4 View

Is it necessary to report effect size (ES) in statistics of biomedical research given that we already report p values routinely?

Pls share your thoughts

01 March 2021 7,330 4 View

What is the most reliable source to get Impact factor of journals?

Source to get Impact factor of journals

01 March 2021 6,654 2 View

Can anyone help me with the administration of the "Mind the Gap" Scale for satisfaction with transition to adult care?

We are working on a study focused on adolescents' transition to adult care and are looking for a validated measure for satisfaction with the transition. So far the only measure that we have came...

28 February 2021 2,338 1 View

How to calculate Ligand-active site distance in a ligand-protein complex from MD simulation?

I have run a MD simulation of a ligand-protein complex in GROMACS using CHARMM forcefield. Reviewer has asked me to calculate Ligand-activesite distance and binding free energy of ligand with...

27 February 2021 4,703 1 View

Which index or sites are reliable in determining of plant species?

There are many indexes when determining plant species: Plants of the World Online (POWO), International Plants Names Index (www.ipni.org), The Plant List (www.theplantlist.org) and others. But...

26 February 2021 3,404 10 View

Is there an open source free software for text mining and sentiment analysis?

I am looking for a free software for text mining and sentiment analysis for my research on customer review mining (it involves calculating polarity of attributes,opinion oriented information...

25 February 2021 1,920 6 View

Which are the journals for free paper publication?

A bunch of flower for everybody. I would like to ask about the list of journals which we can publish our paper for free. Thanks in advance. Sincerely Walid

25 February 2021 9,790 3 View

Suggestions for occupational stress surveys?

I am currently writing a masters thesis on reasons for occupational stress in the early childhood classroom, and want to include a short survey assessing participants work-related stress levels. I...

24 February 2021 8,678 2 View