Toxoplasma gondi is opportunistically, it activates when the immune landing.

Yes I think there is association between it and hormones mainly

Cortisol and prolactin

I don't know what the answer is offhand (don't work on Toxoplasma anymore), but either a pregnant woman's T-helper cell type 2 (Th2) immune profile might have something to do with it, or not. Possibly not. Certainly, immunity (not necessarily Th2, which is characteristic of helminthic infections) is important in toxoplasmosis though, i.e. in the context of immunodeficiency.

During pregnancy and lactation periods, the prolactin hormone is increasing, which decreases the body's immune system and increases toxoplasma activity.

Thanks a lot for your valid answers.

In addition to the evidence based responses provided by other eminent researchers in medical parasitology, I wish to state that the parasite in question is an opportunistic parasite that probably operates very freely in immuno-compromised subjects and those on steroid drugs. However, pregnancy comes with Vulnerability to large arrays of infections, coupled with the physiological changes that appears very visible during the period. Thus, there seems to be an increase of the parasite burden during the second and third quarter of pregnancy period which could probably be linked to simultaneously progesterone and 17β-estradiol substantial amount increase . However, it is firmly believed that the presence of the parasite during pregnancy at the above stage slows down inflammatory responses of body defenses mechanisms, hence providing good ground for the parasite to multiply.. Lastly in other hand it is also believed that the increase in the susceptibility of the subjects and the marks decline in the pro-inflammatory responses could cause unfavorable environment for the growth of the parasite during pregnancy

Thank you so much for your valid answer.

Yes, there is marked relationship with respect to the presence of the hormone that are associated with pregnancy and an increase in infectivity pattern and pathogenicity of the said parasite

Thanks a million.

I am so grateful to all colleagues who responded to my question.

Kindly see the following RG link.

Article The role of hormones on Toxoplasma gondii infection: a syste...

Gloria NGOZIKA Professor Wokem

please check the pdf