I am wondering whether it is possible for healthy young adults to exhibit negative cortisol awakening response (CAR) (cortisol level 30min after awakening lower than cortisol level at awakening) or if on the contrary negative CARs are for sure due to non-compliance. In this latter case should negative CARs be discarded from further analyses?
here you are email-adresses to persons who can give you a good answer:
E-mail addresses: [email protected] (A. Gonzalez), [email protected] (J.M. Jenkins), [email protected] (M. Steiner), afl[email protected] (A.S. Fleming).
Hi Patrick,
I've attached a PDF that may help. In addition to CAR data, the author also has ECG/motility data to show when the individual actually woke up. They conclude: "These observations indicate that waking up earlier than reported was indeed responsible for the majority of the apparent negative cortisol awakening responses. Because the awakening response was assessed incorrectly in these subjects that showed a negative CAR, their awakening response samples were excluded from further analyses."
Hope that helps!
Danielle
https://pure.uvt.nl/ws/files/989737/proefschrift_Kupper.pdf
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