I'm about to start a systematic review of studies on Type-2 diabetes. This will include an estimation of the severity of the studies based on the reported phenotype and a few other factors.
I have had difficulty finding good references on clinical signs of disease that signal poor health and welfare. Do you know of any good reference on this?
Alternatively, I would very much thank if someone could provide any information on animal health/welfare status as a function of glicaemic levels or other parameters.
I think the following article will help you.
http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003149
http://dmm.biologists.org/content/10/2/151
In this reference, researchers studied on the survival rate and prevent glucose tolerance by inducing the diabetes after feeding the Guinea-pigs with high fat and carbohydrate diet for several weeks. Survival is essential for health and welfare ..
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