The parenteral synthetic anticoagulants are argatroban, bivalirudin and fondaparinux. Argatroban and bivalirudin are parenteral direct inhibitors of the activity of thrombin, but, unlike heparin, can inhibit both soluble as well as clot-bound thrombin. Fondaparinux is an anti Xa anticoagulant. All heparins derive from porcine intestine. As far as I know, synthetic heparins are not on the market Article The design and synthesis of new synthetic low molecular weig...

Good luck with your study!

Pentosanpolysulfat SP 54?

Hello Silvia Clapauch ,

Thank you for your answer!

I apologise for the late reply. I have heard of Fondaparinux too. Aren't all three anticoagulants you mentioned, on the market?

All best,

Alexandra

Hello Hans-Jürgen Kolde ,

Thank you for your answser!

I can see that it is being sold as a drug but I could not find any vendors. We would need it in liquid form.

All best,

Alex

You may contact Prof. Rudolf Gruber at Bene Chemie, the manufacturer of SP54 and derivatives of it. Mention my name, we are collaborating.

[email protected]

Fondaparinux could also be an alternative. It is fully synthetic.

Best regards

Hans-Jürgen

Alexandra Johansson

Hi Alexandra, argatroban is sold in Sweden as Novastan. Bivalirudin is sold under the brand name of Angiox (if not, try Angiomax). The brand name of fondaparinux is Arixtra.

Best wishes.

Hans-Jürgen Kolde How kind of you.

Thank you very much!

All best,

Alexandra

Hello Silvia Clapauch ,

Good to know! Thank you for all the information.

All best,

Alexandra