introns
metformin a drug that used to reduce the insulin in peripheral blood of patients with PCOS and then reduce of endrogen ; how the metformin reduce the INS gene expression ??
16 August 2019 2,712 3 View
07 August 2019 7,877 3 View
methylation is un important process for gene regulation.
06 May 2018 5,554 4 View
It is known that FinFET transistor can be used for ultra low power applications. However, I didn't find any research had used this nanotechnology in the biomedical implant applications . is there...
07 August 2017 5,183 3 View
Dear researchers, LDPC uses matrices multiplication which makes it complex and power consuming. The question is: Is there any version of LDPC that is less complex or any other efficient coding...
01 February 2017 3,886 0 View
Genetics
11 December 2016 4,108 0 View
Dear researchers, I hope you can advise an answer or a reference for the following question: For a normally distributed random process, what is the probability distribution of its upper and...
11 December 2016 3,366 6 View
the title is : Identification of Mutations in the coding region of the Human thyroid peroxidase gene in patients with Hypothyroidism.
11 December 2016 8,376 0 View
Dear researchers, Where the impulsive noise (alpha stable and contaminated Gaussian noise) can be found in real applications? In other words, is there any field where the impulsive noise is used...
31 December 2015 5,663 2 View
What is the effect of mutations that occur in introns?
26 October 2015 6,507 3 View
Hello all, I extracted RNA from my samples and performed RIP-seq. After annotating the genomic regions using R, I obtained promoters, exons, introns, and UTRs. Given that my samples consist of...
18 July 2024 1,579 2 View
Hey! I aim to generate a transgenic knockin zebrafish line that mimetizes a genetic condtition that leads to a certain disease on human. To do so, I need to insert a codon for mutagenic aminoacid...
14 July 2024 6,240 0 View
Studying a specific monogenetic disease based on mutations in different individual genes. I try to recreate the disease phenotypes of donors in vitro. I knocked out a gene x with above 90%...
12 July 2024 6,313 0 View
I have done site-directed mutagenesis (Substitution) to obtain a Cysteine mutation in my gene of interest. Now, I have two domains in my protein, And I want to delete one of the domains to obtain...
05 June 2024 9,430 1 View
Now, I am using CRISPR/Cas 9 system to make a point mutation at THBD gene. I am wondering how can I isolate the desired cell population after making a point mutation by using CRISPR/Cas 9? Are...
30 May 2024 9,993 0 View
We want to suppress self proteolysis of a protein. What is the strategy to modify the sequence in order to make it stable? The site is SLG - NX and SLG - AX.
25 May 2024 7,649 0 View
I am using GraphPad prism for data visualisation and analysis. I am trying to assess if there is a statistically significant difference between the percentage of 2 cohorts (patients and cell...
17 May 2024 4,424 1 View
I am working on a project to detect genetic mutations in lung cancer using machine learning algorithms and I am new to genetics and medical sciences. Can I use RNA as input to the algorithm for...
13 May 2024 5,726 6 View
This is from an endomyocardial biopsy from a 24 year old male with clinical hypertrophic cardiomyopathy. However, no mutation is found in the related genes. What are the irregular nuclear-like...
12 May 2024 8,148 1 View
presently I'm doing one study on ASSOCIATION OF COMT GENE VARIANT WITH ALCOHOL USE DISORDER. the methodology consists of conventional pcr with comt primers and rflp with NIA III rest enzyme. after...
22 April 2024 4,927 3 View
