Any HPLC validated method available to separate tricholine citrate and cyproheptadine hydrochloride from any formulation?

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Andrei Blasko

Cyproheptadine hydrochloride has a monograph in USP-NF. including the analytical method. It is also a Reference Standard. You should be able to separate the two compounds.

www.uspbpep.com/usp29/v29240/usp29nf24s0_m21710.html

Christophe Hano

Dear Swarnalata Joardar

This paper describing a validated method could also be of great help in my opinion:

https://www.sciencedirect.com/science/article/abs/pii/S0731708504001141?via%3Dihub

With kind regards

Christophe