Hi Ajinkya, could you be more clear regarding the meaning of "check my depot formulation"? Are you trying to assess the drug release from the depot? Regards, Luis
YES, I have to assess the drug release from my In Situ Gel Depot Injection. So is there any Ex Vivo Phantom method available to mimic Intra muscular (IM) Route? Luis F. Gouveia
Hi Ajinkya Nitin Nikam Ajinkya, I'm sure there is. The specific conditions are, for sure, product specific as it will depend on the active substance physical-chemical characteristics as well as the ability to detect differences in the release profile after deliberate (or not) changes in the product formula and/or manufacturing. I am not sure of the hardware setup (if it is advisable to use one of the official dissolution apparatus) but I can check if you didn't got the information yet (please let me know).