Any CD8alpha antibodies that do not compete with clone 2.43?

10 October 2017 1 5K Report

Hi all,

I was wondering if anyone know of any CD8alpha antibodies that do not compete for the binding site with clone 2.43? I want to do a depletion study using 2.43 and want to assess the efficiency by doing flow cytometry using a non-competing CD8alpha antibody. I know people have been using CD8beta antibodies but I would like a CD8alpha antibody if possible. Many thanks in advance.

So Ri Jung

For those who follow this question, our research group identified ThermoFisher Scientific's anti-CD8alpha clone 'CT-CD8a' to be suitable as a detection antibody post-depletion with repeated injections with anti-CD8alpha clone '2.43'. For more information, please have a look at our paper:

Article Collateral Damage: What Effect Does Anti-CD4 and Anti-CD8α A...

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