Animal experiments with low pathogenicity avian influenza viruses (LPAIVs) - are there risks for humans?

17 January 2013 1 5K Report

Is it safe to perform experimental infection of poultry with low pathogenicity avian influenza viruses (LPAIVs) in the absence of biosecurity level-3 (BSL-3) facilities? Do they they pose significant risk for humans?

Uttam Patil

Hiii Zaheer

Its not safe to perform animal expts with LPAIVs without proper biosecurity. There is always chance of LPAI to mutate HPAIV. Due to genetic drift and shift, the virus is on regularly evolving itself to adapt host. so that its better to do animal expts in biosecurity level-3 (BSL-3) facilities

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