Other than leptin and ghrelin, what other salivary biomarkers are commonly related with obesity? Thanks.
Adiponectin, Resistin, IL-8, VEGF, MCP-1, CRP, Insulin, IL-1β, MPO, MMP-9, IL-12P70, IL-4, IL-6, IL-13, TNF-alpha, IL-10, IFN-gamma,Leptin, Ghrelin, and IL-17A are used as salivary bio-markers to evaluate metabolic changes associated with obesity
Most of salivary biomarkers are associated with periodontal inflammation. Salivary insulin and ghrelin have been associated with T2D and obesity. Salivary insulin is linearly related to plasma insulin during the glucose tolerance test and correlates well with plasma concentration after insulin injection. Plasma insulin decreases in parallel with weight loss in obese children . Salivary CRP concentration has also been found to correlate well with serum concentrations and it is. Associated with obesity in black South African children . Furthermore, vascular endothelial growth factor (VEGF) was found in saliva of diabetic women . Further information including saliva collection could be obtained from, Goodson et al . Metabolic Disease Risk in Children by Salivary Biomarker Analysis. PLos One 2014;9(6): e98799.
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