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How do different sampling techniques, such as replica exchange MD (REMD) or metadynamics, compare in efficiency and accuracy for estimating binding affinities using endpoints like MM-GBSA, and...
16 August 2025 5,400 0 View
I am currently conducting a research study and am interested in using enalapril as a positive control in my animal model (Wistar rats). Specifically, I am looking for a water-soluble form of...
14 August 2025 4,383 1 View
Can recycled materials achieve similar or superior performance compared to natural aggregates when used as a full replacement in pavement layers?
13 August 2025 4,597 3 View
I am trying to derive the scattering amplitude for two xenon atoms near copper substrate under helium matter waves in the form of beesel beam using partial wave analysis (similar to Messiah's...
12 August 2025 2,395 0 View
I am looking to understand whether Isoflurane can be effectively used with anesthesia machines for administering inhalation general anesthesia in animal models. Are there specific considerations...
12 August 2025 8,478 1 View
I’m using a diabetic nephropathy mouse model and planning to give the drug at 20 mg/kg via IP injection. Do you think normal saline (0.9% NaCl) would work for dissolving it, or should I consider...
08 August 2025 3,038 1 View
We are performing QSAR analysis using Insilco Toxicity Prediction software by using two models viz. Statistical Method and Expert rule based method. I've a question as follows; Compendial...
07 August 2025 3,194 2 View
Hi everyone. I would like to know a good protocol for RNA extraction and real time PCR in C. elegans. In particular, I am asking how many worms are needed for efficient extraction?
05 August 2025 6,724 4 View
Deconstructing the new media era, are the richness of human experience being continuously narrowed by these four key paradoxes - the symbol craze and the language poverty, the convenience of...
04 August 2025 9,227 0 View
Authors (including those) in sexual health research have concerns about peer review suggestions on literature and reviewers' work. Sexual health research, including sexuality education, depends on...
01 August 2025 2,302 6 View
We are working on some simulation based work for solar cells and tried to get the software through mail. But even after a month and multiple mail I have not received any response. Please let me...
01 August 2025 8,254 3 View
I have three kelp, two green, and one red seaweed species that I would like to analyse and quantify for their fatty acid content. I do not intend to differentiate between lipid classes. Would a...
01 August 2025 5,304 0 View
I’m encountering issues while isolating and visualizing plasmid DNA from E. coli. Even after running the gel, I observe either a smear or very faint/unclear bands. I loaded around 7 µL...
30 July 2025 7,209 1 View
Dear colleagues, I am looking for a dataset of children’s drawings that has been labeled for research purposes. All data must be fully anonymized and ethically approved. If you have access to such...
29 July 2025 4,689 0 View
I'm working for my first research paper. I want to use 2 input and 2 output variables with 19 DMUs. My output is general, I mean my output not only influenced by my input. There many factor...
28 July 2025 3,483 2 View
I am currently researching the role of satire in literature and media. I would like to explore how satire functions in American culture, especially in political commentary and social critique, and...
27 July 2025 9,082 0 View
Most literature review used GMM
26 July 2025 3,981 3 View
If an AI says “I’m suffering,” do you believe it? Should we care?
24 July 2025 3,502 2 View
Dear colleagues, I have synthesized anthrone for an experiment, and according to the expected reaction, it should appear yellow. However, the resulting solution is a dark brown color (see attached...
24 July 2025 7,895 2 View
I recently purchased the MCE compound Artemitin (Artemitin), item number: HY-N3017, which belongs to the flavonoids. I would like to ask how to dilute the product in cell experiments? At present,...
22 July 2025 1,010 2 View
The use of time series analysis in forecasting economic trends.
20 July 2025 3,642 13 View
No, for more details, see a standard chemotherapeutic agent, pharmacological justification, pharmacodynamic and pharmacokinetic validation.
17 July 2025 1,733 10 View
I want to work under fake news detected(Networking). Naw I need recent raw data.
16 July 2025 7,751 1 View
Most couples who rate their sex lives highly say they are proactive in sex. They think about when, where and how they’ll have it and think up new things to try. (Tracey Cox)
16 July 2025 677 6 View