Raj Kumar

6 Questions 2 Answers 0 Followers

Questions related from Raj Kumar

Why liposome size not consistant in Malvern zeta sizer nano ZS ?

Hi I am working on liposome formulation. we are trying for reproduction of the size at range of +or- 20 nm. but Malvern zeta Sizer always showing different size with 2-3 peaks always. There are...

19 September 2023 3,293 2 View

What is the best in-vitro model for nitroso compound formation in stomach ? how to study if you developed formulation to inhibit the formation ?

Hi, global research concluded that nitroso compound formation in the stomach is the reason for gastric cancer. We developed a formulation for treatment. We would like to conduct an in-vitro model...

02 March 2023 8,519 0 View

Can i get the detail protocol for processing and cross sectioning of colon for H&E and immune staining?

If anyone has experience with what to do or detail protocol from harvesting the colon from mice after sacrifice to preparing the tissue section slides and staining? if any references please...

10 February 2023 1,489 3 View

Why we won't get peak of drug in FTIR of drug loaded polymeric nanoparticles ?

Hi I have done the FTIR of pure drug, pure polymer, and drug-loaded polymeric nanoparticles. But I did not get any drug-related peaks in FTIR or drug-loaded polymeric nanoparticles. Can any help...

01 January 1970 4,962 3 View

Can we study the stability of siRNA in a formulation containing siRNA and drug loaded polymeric/carbohydrate polymer?

Hi, I would like to study the stability of siRNA after loading into the formulations such as siRNA and drug-loaded polymer/polysaccharide nanoparticles. Is CD suitable? Does it predict the...

01 January 1970 818 1 View

Is any method or technology for liposome production with reproducible at industrial scale

I was instructed by my boss to try reproducible liposome using different techniques. the size varies from 30 nm to 110 nm, when repeated. my boss keep pushing me to work hard to reproduce but it...

01 January 1970 1,295 5 View