16 Questions 60 Answers 0 Followers
Questions related from Melvin Hayden
Recently, I was introduced to perivascular spaces (PVS) while studying lipopolysaccharide treated models with transmission electron microscopy (TEM). Erickson MA, Shulyatnikova T, Banks WA,...
17 February 2023 2,498 7 View
Soon I will be writing a paper on IMPAIRED Folate-mediated One-Carbon Metabolism (FOCM) in COVID-19, and I will be needing input from a vast array of scientists and researchers who are interested...
26 September 2021 4,490 3 View
I have a 76 y/o male patient with history of low HDL-C who had an myocardial infarction in 1997. He has done well following a program of dietary changes and exercise but has not quit smoking. He...
22 January 2021 6,066 4 View
The process of viremia involving the transfer of the whole virus from pulmonary alveolar epithelial pneumocytes to the alveolar capillaries and hence to the systemic circulation is not well...
08 October 2020 899 6 View
We have known for some time that the visceral adipose tissue plays an important role regarding the metabolic syndrome and type2 diabetes mellitus (T2DM); however, the finding that ACE2 staining is...
09 August 2020 6,596 4 View
Indeed, there is a bidirectional relationship between Covid-19 and diabetes and since my interests have always been in the field of MetS and type 2 diabetes mellitus (T2DM) I pose this question...
26 June 2020 2,369 5 View
It is becoming more and more clear that males are at a greater risk of developing infections with COVID-19 and are at a greater risk of morbidity and mortality. This is open to thoughts...
22 March 2020 3,937 8 View
Repurposing of Sodium Thiosulfate (STS) in the treatment of COVID 19 or SARS Cov-2 Viral pandemic of 2019-2020 Repurposing or repositioning of medications to treat emerging diseases is not a new...
21 March 2020 2,753 15 View
We wish to see if the endothelial glycocalyx is decreased in diabetic models and excess sodium models and we wanted to know if anyone had any suggestions for additive stains to standard TEM...
28 May 2018 3,353 5 View
I am currently studying the db/db K strain and have a project with updates regarding my transmission electron microscopic findings and I have found that in this obese insulin resistant model with...
06 November 2017 2,945 1 View
I recently found out that Mazucanti CH et al had discovered that insulin was synthesized in the choroid plexus within ependymal cells of the brain. I was very excited to learn this as a source...
01 January 1970 9,756 6 View
I have noticed an increased in the asymmetrical synaptic excitatory junctions to be increased in the diabetic brain but could not find any discussion of this in the literature at present. If you...
01 January 1970 4,099 5 View
Because the endothelial glycocalyx may be attenuated and or lost due to multiple metabolic toxicities in the intersection between Type 2 Diabetes and Met S in COVID-19 and the endothelial...
01 January 1970 6,910 3 View
The red blood cells contain a full complement of sodium transporters and cotransporters and since the RBC plasma membranes were utilized initially in the early studies of sodium transport, I am...
01 January 1970 6,944 9 View
Dear friends and colleagues, I have recently found definite extracellular nanometer vesicles (60-70nm in diameter) being extruded from rupture-prone adipocytes and crown-like structure...
01 January 1970 5,213 0 View
I wish to open a discussion regarding the increased risk of late-onset Alzheimer's disease (LOAD) in those patients with pre-existing type 2 diabetes mellitus (T2DM). I am contemplating writing...
01 January 1970 5,536 5 View