15 Questions 21 Answers 0 Followers
Questions related from Chiranjeev Sharma
How can compounds with minimal or no UV absorption be effectively detected and monitored during liquid chromatography (normal or reversed-phase) purification? I am particularly interested in...
15 November 2024 9,966 6 View
A classical statement of the basic good will in The Hindu View of Life (by S. Radha- krishnan, p. 92) occurs "in the sublime verse of the Bhagavata: 'I desire not the state [of bliss] with its...
17 May 2022 4,014 2 View
Hi, I have installed an Autodock 1.5.7, I have also installed MGL tools. But as soon as I open the protein file in Autodock tools and add hydrogen, the autodock window closes. I assume I have a...
28 August 2020 5,032 5 View
Hi, does anyone know any reference for an anticancer PNA with nM activity? I found several antisenses and antigene PNAs studied for the development of the anticancer drug. However, the IC50 value...
25 August 2020 536 0 View
The supreme property of chemical matter is its potency to have given rise to the emergence of life. Yet life’s origin continues to be one of the big unanswered questions of natural science. How...
19 April 2016 369 2 View
A compound crystallizes in C2 space group and it has axial chirality. How can we prove that it comes from spontaneous resolution? Should we expect different conformations (Delta and Lambda) for...
14 March 2015 2,267 5 View
We have crystallized some bioactive organic molecules. On the basis of van der Waals radius of oxygen we found them to possess remarkably short intramolecular oxygen oxygen interaction. Is IR and...
26 November 2014 7,534 1 View
If a compound dissolves by heating any compound till it's melting or to its boiling point in any solvent, can we say it's soluble? Is there some relation between the concept of saturation,...
16 October 2014 6,212 4 View
why 13C NMR is done at lower frequency as compared to 1H NMR?
15 October 2014 7,340 19 View
I need to synthesize alpha beta unsaturated isoleucine and valine. Can anyone tell me some easy synthetic strategy to do so, along with the reference for that method.
24 September 2014 4,539 2 View
While working on peptides, we protected the amino acids and peptides. Even the very basic Boc protected Valine or Tyrosine is a thick oil which we use in the next step without purification. Even...
06 August 2014 9,750 3 View
Could organic peroxides have some role in the origin of life? Can we have some critical and rigorous discussion whether in favor or against any role of peroxide in origin of life.
08 May 2014 6,694 2 View
Is it with respect to the catalyst or the weight of the catalyst divided by its molecular weight. Actually we are synthesizing Tetrazoles from Benzonitriles. 100 mg of benzonitrile was reacted...
26 April 2014 9,784 7 View
I've been working on acyclic, cyclic, and oligomers of organic peroxides for the last three years. Although all literature reports do mention that these are potentially explosive, there aren't...
11 March 2014 2,582 16 View
I've been working on cyclic peroxides esp. tetraoxanes for past two and half years. I've characterized my compounds using IR, Raman, 1H and 13C NMR. I've also used X-ray crystallography to solve...
29 November 2013 279 8 View
