Alex Thomas

13 Questions 10 Answers 0 Followers

Questions related from Alex Thomas

Which is best statistical model for randomization in respect to animal studies?

Pls discuss, stratified randomization and excel method leads to accumulation of group having all the less body weight animals

08 August 2016 7,718 5 View

Suggest a method to obtain sample for MPCA enumeration from organ/tissue without disturbing spore?

As per the OPPTS 885.3050 it is stated that One should perform MPCA enumeration in tissues and Organs, as homogenization of tissue/organ can disturb spores. pls suggest a better method

07 July 2016 7,692 0 View

Toxicology of Herbal extracts, which will be an ideal guideline and why?

03 March 2016 5,206 3 View

Which type of statistcal analysis can be done for FOB (functional observational battery) data for sube acute toxicity study in Wistar rats?

Study Name : Sub acute toxicity Groups: 6 groups G1 control G2 low dose G3 mid dose G4 high dose G 1R control recovery (satellite group) G 4R high dose recovery (satellite group) observations...

01 January 2016 3,524 3 View

How can I calculate Cmax, Tmax, AUC, T1/2 in PK/PD studies?

Please find the data below: TIME IN MIN - 0, 30,60,180,300CON OF CURCUMIN in µg - 0.00, 7.66, 84.27, 40.87, 7.84 respectively

01 January 2016 7,387 6 View

While we performed an ethanol induced hepatotoxicity study we found a balloon like stomach and intestine in a rat and it died. Any explanation?

It happened after week of induction

11 November 2015 929 7 View

1,2,6 Hexanetriol is consumable?

please refer the link

10 October 2015 9,310 0 View

What are the hall marks of Ethanol induced hepatotoxicity?

10 October 2015 1,067 0 View

Can anyone advise me on food grade glue?

we are developing a kitchen utensil, which is made by wood please tell about a glue to stick the same with out any toxicity when ingested.

08 August 2015 8,157 4 View

Will a 20% glucose feeding reverse the STZ (65mg/kg) action in rats?

I have administered STZ (65mg/kg) and given 200 ml of water with 20% glucose overnight, when i checked the blood glucose levels after 72 hours of STZ administration every rats were normal

04 April 2015 2,180 20 View

What should I consider while injecting STZ for inducing diabetes in rats?

Ideal dose of stz Glucose feeding Body weight Vehicle

04 April 2015 1,083 4 View

How can I reduce mortality in STZ induced type II diabetes in wistar rats?

Dose injected - STZ 60mg/kg I.P Strain: wistar albino female rats Bwt-120 to 150g have given 5%glucose 2hr after STZ induction for 24hours ...

04 April 2015 2,886 15 View

Can anyone suggest a pharmacological screening method to compare activity of plant extract against uric acid and calcium oxalate stones in rats?

I would like to make a comparative study on the effect of a plant extract on uric acid and calcium oxalate stone in vivo.

03 March 2015 9,808 4 View