Abdelaziz Ghanemi

9 Questions 24 Answers 0 Followers

Questions related from Abdelaziz Ghanemi

Metabolism of mice ?

Compared to humans, what are the metabolic (biochemical) features and differences ? What is important when we study the metabolic of mice and want to extrapolate to humans ?

10 October 2014 2,570 0 View

How can you decide drug quantities given to mice based on the weight of the animal?

Since the drug quantity given to mice depends on the animal weight: 1. How often we have to weigh the animal to adjust? Once a week? 2. Is it acceptable if in the same group that has around 8 mice...

10 October 2014 9,185 5 View

Can anyone provide advice on the study of APOE transgenic cell lines ?

To study Alzheimer's disease , I need to study the involvement of APOE genes in Amyloid Beta production thus, I am searching for suitable cell lines that specifically express these genes (APOE 2,...

09 September 2014 2,497 2 View

Can we extrapolate pharmacological data from mice to rats and vice versa?

When we have a therapeutic dose of a compound and also its LD measured in rats can we use it when we design an experiment on mice ? (And vice versa)

09 September 2014 2,071 10 View

What would be the best animal model to study drug effects on Alzheimer's Disease?

If we have to select an animal to study either the effect of some drugs on Alzheimer's disease what would be the best choice ? Mice ? Rats ? Others ? Why ?

09 September 2014 2,165 4 View

What is the best animal choice?

For a pharmacological and another pathway study related to Alzheimer's disease (such as those including building animal models), what is the best animal choice? The mice or the rats? If it is the...

09 September 2014 7,558 6 View

Do you have protocols of primary cells cultures of hippocampal and cortical cells respectively (taken from monkey brain)?

See above

08 August 2014 903 1 View

What are the best choices for the cell culture to study Alzheimer's disease?

I plan to investigate the implications of a compound in Alzheimer's disease and conduct some pharmacological tests. What is the cell line（s） you suggest me to use?

08 August 2014 1,972 8 View

What are the best choices for the Cell culture to study Alzheimer;s disease ?

What are the est cell lines to use to study AD in cell cultures (In vitro)?

08 August 2014 5,307 2 View