We are a consortium of scientist from Kenya, Tanzania and South Africa with interest on water related research. We have developed a concept proposal on disinfectant by products (DBP), our main concern is the growing number of cancer cases being witnessed in a number of African cities. The concept seeks to profile NOM and DBP and assess the mutagenic activity of some of the common DBP. We will apply multivariate techniques to determine the most influencing parameter in formation of DBP for specific water sources. And ultimately develop a mechanistic model to inform on DBP.