Hello every one,
I want to compare my diseased samples (metagenomic sequences)with control samples already studied in the past. I have also sequenced control samples but not in enough numbers that can give me more deep idea about diseased mechanism. The study I want to compare was sequenced with same 16S hypervariable region so there won't be any biases which can affect comparison efficiency. So my question is comparing my data with the past study and writing research paper based on that results will decreases weightage of research paper? Will it decreases research paper quality? Moreover I already compare and analyzed it and it has provided a very sound background to proposed mechanism for initialization of pathogenic condition. So I though better to ask views of scientific community before writing a manuscript.
Thank you very much for the time
Regards
Hello Lucia,
Thank you very much for your valuable suggestion. I will keep in mind.
Cheers,
Shriram
Hello
to enhance your study, you can use 'Kalman Filter' this takes into account the existent data and update the latest data.
Dear Gretete Driss,
As per your suggestion I have gone through basic introduction to "Kalman Filter". Idea is quite interesting and I am really excited to know that how I can use it to compare results of different metagenomic study? Can you please brief me about that. I will be thankful if you can attach some papers related to this.
Thank You
Shriram
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