Besides an anti-diabetic drug, Metformin is used broadly in treating polycystic ovary syndrome (PCOS). Newer studies have shown a potential chance for growing gestational diabetes if a huge amount of fried food intake happens in prepragnancy. For the remedy or prophylaxis of that gestational diabetes, Metformin is a good choice. Now the major concern is what will be the efficacy as well as logic of using Metformin in that case.
http://www.medscape.com/viewarticle/833347?nlid=67783_2843&src=wnl_edit_dail&uac=230856SK
http://www.ncbi.nlm.nih.gov/pubmed/25013215
http://www.ncbi.nlm.nih.gov/pubmed/24271189
evolution of science shows that plysiology is tight in pregnancy so I medical jugment should be diet of marine origin to overcome adverse effects of gestational diabetes promoting the physiologic role of iodine in global metabolism.
take care of transgenerational action by testing rats for exemple
Do you know that metformin supresses the growth of stem cells. Isn't it harmful ?
Dear Igor Lakhno, It's true that metformin can be used against cancer due to its effect against stem cell suppression, and more severely it can be teratogenic in first trimester, though we haven't much supportive data yet. Things we have to concern the both- advantages and side effects. Those attachments could have settle you in more dilemma.
http://www.healthline.com/health-blogs/fruit-womb/metformin-use-during-conception-and-pregnancy
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493830/
Reduce the intake of fried foods to control growing gestational diabetes. Excercise along with metformin is a good remedy in this case.
There is very little evidence to support the use of metformin to prevent progression to diabetes or to prevent GDM in patients with PCOS. The cornerstone of therapy must remain lifestyle improvements including a proper eating plan and exercise. The use of any pharmacotherapy should be contemplated in addition to, and not instead of, lifestyle improvements, if indeed there is any reason to use it at all in this situation.