This is true, but there are no better alternatives. The growth if within 6 months means on the other hand quite aggressive tumoral behaviour and thus chemotherapy works reasonably well.

This is true, but there are no better alternatives. The growth if within 6 months means on the other hand quite aggressive tumoral behaviour and thus chemotherapy works reasonably well.

Chemotherapy is not site specific. But gold nanoparticle encapsulated chemotherapies have better success to reach cancer cells. You can contact with cancer research institute for this. Besides you can use immunotherapy, and you may contact Dana-Ferber www.dana-farber.org. However, chemotherapy will not give benefit rather it will deviate the situation more and more. It can extend the life for a while. 

Other more options are, you can use catheter delivery ablation methods for chemotherapy or biopsy. In addition, you can use antiangiogenic therapy to stop the cancer progress. We have many alternatives and it is needed to read the history of patient. If it is early stage even little metastatic progression, we are sure that we can save this patient. 

Spatial resistance to chemotherapy is the main concern, I agree. But post-radical radiotherapy chemotherapy may be effective to control tumors existing beyond the radiation field in some patients. Whether it will help consolidate local control of the irradiated esophageal tumor is truly questionable.

Combination of  chemotherapy and  is the best treatment of esophageal cancer

After radiotherapy, Systemic chemotherapy is mandatory  to reach residual  esophageal  cancer cells.