why worms do not destroy with antibodies or phagocytosis.
Too big for phagocytosis!
The antibodies involved together with eosinophil in the removing of worms through a process of ADCC.
Some of them are destroyed, on the other hand others are not.
Nemanja's answer above is correct-helminths as multicellular organisms are simple too large to be phagocytosed by PMN or macrophage. The classical anti-helminthic response are IgA or IgE antibodies with eosniphils as the effector of ADCC. In the case of helminths eosinophils degranulate onto the worm surface causing damage. IgE is particularly good at ADCC as it has two Fc receptors rather than the one of most Ig classes.
hi
because are very large in size than the macrophage , IgE very good at ADCC DUE TO HAVE 2 Fc receptor .good luck
- Badges
- Science topic
- Similar topics
- Biological Science
- Immunology
- Antibodies