Why tRNA and rRNA don't require 5' mRNA capping for stability like mRNA does?

02 June 2016 1 1K Report

What stabilises these RNAs?

Dear Jatin Sharma

One reasons of the capping, protection of mRNA from attack of 5' exonuclease enzymes. Because, remove only one nucleotide from mRNA, produce inefficient protein. Therefore, preservation of mRNA sequence in tranlation is very important. In comparision with mRNA, tRNA and rRNA sequences are not important.

Best, Roshdi

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