Why Taxol (paclitaxel) color varies on TLC?

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Madhukar Baburao Deshmukh

Taxol (paclitaxel) color vary on TLC because it may form a complex with binder that being charge transfer the colour may vary.

Ravi Kant Upadhyay

Yellow color of the compound is formed due to three reasons, one effect of heat, photoactivation and addition of developer group to the spot. Though it is true it may form complex due to effect of heat and photoradiation.

El-Sayed Ramadan El-Sayed

i mean that under all the constant conditions the color vary from a TLC to another for the same fungal extract and standard. sometimes appears blue-green others violet.

Jai Ghosh

Just check the molecular weight along with the Rf values and you will see that the compound has undergone some sort of degradation.