Dear it could be that host cells recognize such easily and produce enough antibodies without delay that mount immediate denfense.

Depending on the strength of the immune response, the types of immune cells involved and the ability of the virus to evade the body's defense, infection can either lead to clearance (acute disease) or persistence (chronic disease) of the virus, such may be the case in hepatitis.

Again, meanwhile infection does not directly trigger apoptosis (known as cell death) but through host immune response by triggering a number of inflammatory responses, therefore in a number of cases such as immunocompromised individuals in addition to an agents which evade body defence through their antigenicity types, one may expect chronic disease (and this context, a chronic hepatitis).

Kamoru A. Adedokun Many thanks for your contribution. The main component of the immune response against all hepatitis viruses seems to be cytotoxic T cells. That is why liver pathology looks similar regardless of the virus. Why in A it is cleared perfectly and in most cases of B and C despite that fact that the immune system is functioning well as evidence by the liver damage in the acute stage.

Thanks again

Emmanuel Ifeanyi Obeagu Thank you. Defective interfering particles produced during viral replication are though to greatly contribute to spontaneous regression of viral infections.