Hello Raj,

I'm not a specialist in the field, but if you read through the abstract of this article, it seems clear that they use Nisin because it increases the stability of pores in liposomes after Electroporation (EP). Thanks to this property, the electric field to induce pore formation in liposomes is reduced in a way that it may be applied in vivo. Therefore, this formulation (nisin+liposomes containing drug) could be used to develop drug-delivery systems upon local (such as around a tumor) electric stimulation.

As for the sequence, you may read this article (attached file), where a certain number of nisin variants are compared. I suppose that the reference sequence is that of Nisin A.

You might also take a look at wikipedia: http://en.wikipedia.org/wiki/Nisin

Good luck with your research...

Dear Dr. Leonardo,

Greetings!

Many thanks for your detailed description of the answer for my question. Now, i am cleared the purpose of the study. You are really helpful.

Many thanks,

Raj