Conservation
In mammals the structure of pituitary GH is
generally strongly conserved, indicating a slow basal
rate of molecular evolution. However, on two
occasions, during the evolution of primates and of
artiodactyls, the rate of evolution has increased
dramatically (25- to 50-fold) so that the sequences
of human and ruminant GHs diVer markedly from
those of other mammalian GHs.
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