In a recent experimentation where we tested an agent's effect on the oxidative stress status on mice (inflammatory model of IBD), we found that livers and colons present a similar response plot.
In the aim to dig deeper, we tried to test our agent on mitochondrial swelling (in vitro). We were surprised to find that low doses induced a significant decrease in Liver mitochondrial activity compared to colons, which were not affected.
any speculation regarding this phenomena is deeply appreciated.
PS: The agent used has a metalloid characteristics.