Kindly share your knowledge on the question. Thanks.
Hello We are looking forward to buying the best gold nuggets and other gold form detectors. Additionally, if it detects other metals, that will be an added advantage. We do not want to scan it a...
10 May 2024 1,767 0 View
Dear connections I want to perform scaffold hopping of some molecule to get novelty on the reported compound can you suggest me the best software for the same. your support will be appreciated...
01 May 2024 5,864 1 View
I want to perform synthesis of reported compound can you suggest some techniques to find novel compound with better results
01 May 2024 5,935 2 View
can you suggest any schrodinger interface for scaffold hopping
01 May 2024 1,351 0 View
I have a reference and hit molecules. I need to compare and differentiate the scaffolds present in this hit molecules. my aim is to identify which scaffold that plays a significant role in AD.
01 May 2024 6,562 0 View
I am conducting a study where 4 groups are measured over 4 different time points (t0, t30, t60 and t90). I am mainly interested in what happens within groups. I am carrying out RM_ANOVA, I got the...
19 November 2023 9,012 8 View
Required for a project ASAP!!!
26 April 2023 6,725 1 View
I am studying microbial diversity and wants to know which culture media should I use to get a better understanding of microbial diversity
10 March 2023 8,662 1 View
ACI code has 0.25l edge reinforcement but BS8110 and IS sp 34 has only 01l as full fixity monolithic beam slab.
05 June 2022 933 0 View
Why is RNA getting separated to the aqueous phase from DNA during TRIzol Method. Both DNA and RNA are negatively charged due to the presence of phosphate groups. How does the acidic condition (low...
06 December 2021 7,790 2 View
Hello, I am currently having problems with RNA extraction. I am using mouse liver (C57BL6J), and I have extracted RNA from mouse liver before. Before this experiment, my final RNA pellets were...
11 August 2024 7,082 3 View
Can anyone share any reference that gives mouse specific CD3 antibody sequence. I have been searching for this since few days and no luck. Thank you very much
08 August 2024 9,157 4 View
Hi all, I was just wondering if anyone has experience with multiplexing a mouse monoclonal primary and a rat primary. I'm trying to multiplex by incubating them in the same well but was told by a...
06 August 2024 9,710 1 View
i have sorted anti-NP specific plasma cells from bone marrow of C57BL/6 mice at certain times after immunization with variable counts and isolated total RNA using TRIZOL method for RT-PCR using...
05 August 2024 8,835 1 View
I have tried several times to isolate lymphocytes from mouse spleen, but all attempts have been unsuccessful. I tried most available protocols. I used different dissociation media (HBSS with Ca...
04 August 2024 9,913 7 View
I´ve been unable to find specific information about this neurotrophin in the CNS of rabbits exclusively. There is extensive info in mice, fish and rats, but in brain´s rabbit is hard to find....
04 August 2024 762 1 View
what are the top 3 challenges to the advancement of the field of Radiogenomics in cancer research? is it the availability of easily available low-cost matched imaging and biosamples with clinical...
03 August 2024 5,828 4 View
I need to lyse and homogenise mouse tissues. So far I have experimented with liver and lung tissue, using matrix D. The liver was completely lysed with 6 repetitions of the standard program, but...
31 July 2024 9,186 0 View
I need to Postfix mice brains. I slice the brains using microtome at 40 microns. These are Postnatal days 7, 11, 14, and 21. I am using half the brain for other analysis, so I need to fresh freeze...
31 July 2024 1,123 4 View
We have encountered an issue with the serum of mice being hemolyzed after the process of centrifugation. Could you please provide guidance to prevent hemolysis ?
29 July 2024 8,402 4 View