troponin I and T are structural cardiac muscle proteins that are released during myocyte damage and necrosis and represent the cornor stone in diagnosis of acute MI
1) How can CVM experts diagnose definitively if the patients have MI, CVM or even arrhythmia maladies considering
Universal definition of myocardial infarction
Detection of rise and/or fall of cardiac biomarker values (preferably troponin) with at least one value above the 99th percentile of the upper reference limit and with at least one of the following:
Symptoms of ischaemia;
New or presumably new significant ST-T changes or new LBBB; Development of pathological Q waves in the ECG;
Imaging evidence of new loss of viable myocardium, or new regional wall motion abnormality;
Identification of an intracoronary thrombus by angiography or autopsy.
Cardiac death with symptoms suggestive of myocardial ischaemia, and presumably new ECG changes or new LBBB, but death occurring before blood cardiac biomarkers values are released or before cardiac biomarker values would be increased.
Stent thrombosis associated with MI when detected by coronary angiography or autopsy in the setting of myocardial ischaemia and with a rise and/or fall of cardiac biomarker values with at least one value above the 99th percentile URL.
You ask medical history: for typical angina, for history of coronary diseases, is patient in high risk (Diabetes, hypertension, age, male, se cholesterol, LDL, HDL, Triglicerid).
You can measure serial of Troponins for decetect is there any change
Consider all PMH have been recorded and everything pointed towards low risk patient (non-diabetic, 50 yo female but with atypical chest pain, with hypertension, low lipid panel) in the midst of acquiring cvm-related illness owing to frequent atypical chest pain.
Interventions have yet to be started except for the EKG or ECG and CE simultaneous check.
Ischaemia is not in the picture yet, what more MI. By tracing both and the t-trop is