How can one synthesize the Inverted Core-Shell Particles (ICS)?

Dear RG colleagues, how can one synthesize the inverted core-shell particles (ICS) from a polymer and a Nano-metal oxide? Where the polymer is a core and the metal oxide is a shell. Under which...

01 December 2020 9,895 2 View

Why does not codeine produce analgesic effect when taken by a patient suffering from dental pain?

codeine is an opioid drug

12 October 2017 8,330 2 View

How can i induce experimental salmonellosis in mice?

using S. typhimurium

03 April 2017 4,485 4 View

What is effective dose of garlic powder when used as feed additive for poultry food?

garlic powder

03 April 2017 2,574 2 View

What is the scientific method for preparation of penicillin in the lab of undergraduate students?

methods with references please

03 April 2017 5,578 1 View

What are the best methods used for identification of glycosides in herbal extracts?

i found this one: 2 ml plant extract was added to 2 ml ofchloroform. Carefully added 2 ml of sulphuric acid and shakengently. A reddish brown colouration was indicated the presenceof a steroidal...

19 March 2017 1,290 5 View

What are the recently used herbal medicines for management of H. pylori infection?

02 March 2017 5,984 3 View

KIRBY-BAUER chart for sensitivity and resistance of bacteria to nearly all the known antibiotics?

02 March 2017 7,574 6 View

What properties in drugs make them addicting?

those drugs act on the brain in different ways

02 March 2017 510 0 View

How can i prepare antibiotic discs from medicinal plant extract?

these discs are used for evaluation of sensitivity test in vitro

02 March 2017 1,565 1 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

How do I choose contrasts in SPM8?

I am learning how to use SPM for PET and PET-MR analysis, but I haven't found any great resources that explain how contrasts work. I have a series of PET images where our hypothesis argues that...

24 February 2021 1,534 2 View

Does anyone have any ideas why drug-resistant malaria is increasing in Southeast Asia even when those drugs are no longer used?

When dealing with bacterial toxins, there are three varieties of microbes that develop in your petri dish: toxic, resistant, and susceptible. Initially, there are only toxic and vulnerable...

21 February 2021 6,084 5 View

What is the most prevalent drug related problem in the developed countries?

Detecting the drug related problems is an important step in the pharmaceutical care plan

21 February 2021 5,421 3 View

No title

19 February 2021 8,647 3 View

How to improve dissolution of neosome?

I have made neosome from herbal drug. Neosomes are stable. But I face problems in dissolution. I used minimum ratio of 1:1:0.25 ( Drug:span 60: Cholesterol and GMs. Now how can I active better...

17 February 2021 3,584 1 View

How to determine the drug loading and the drug release capacity of a polymer micelle using UV spectroscopy?

Currently, I am working on PLA-PEG copolymer micelle for the drug delivery system. I have seen several papers where some researcher talks to centrifuge the drug-loaded micelle to separate the...

13 February 2021 5,822 7 View

Should the AUC in a concentration-time graph of a subcutaneous implant be roughly the same for poeple?

I have 2 concentration time curves of a subcut drug implant. the first group has a peak around the 50 day mark where as the second group does not. Both groups received the same implant by the same...

10 February 2021 2,305 3 View

How can I add the metal oxide NP's to the cell lines? I have to make some drug and NP conjuhgates. How much concentration to use? Need some help?

Hi everyone. I am working on metal oxides. I need to make some conjugates of drugs and NP. But I am unsure of what concentrations to make. I have read some articles, but they haven't mentioned...

10 February 2021 3,372 2 View