Why did A549 Cell Viability Increase upon treatment with p53 activator drug RITA?

10 January 2018 1 8K Report

I treated wild type A549 cells with 10 nM RITA, a p53 activator drug, and the cell viability increased 18.7% in a statistically significant manner (p

Agnieszka Bojko

Probably due to transient cell cycle arrest, in which repair machinery is active, what leads to sorting out the DNA damage and giving the time to cell recovery.

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