Most of the main chaperones(such as GroEL, HSP60 etc.) use cycles of ATP binding and hydrolysis to assist nascent proteins to reach their native fold. The in and out cycle of the nasent protein in the chaperones looks as a periodic function， therefore，could we consider this process as a kind of a signal processing and describe it by Fourier transform?
Georgios Papadopoulos
Dear Xiao, a Fourier Transform would transform a time dependent variable (for example the concentration of the folded protein) to a frequency dependent one. It is possible if you know the time course of the concentration. However, I don't know how it would help further your research.
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