I'm looking for references on prognostic factors that predict recurrence site in endometrial carcinoma. Preferably review articles but all studies are welcome. I've found many studies on prognostic factors for survival after a recurrence but very few that look into factors that could predict recurrence site already at the time of diagnosis. I'm interested in genetic, histopathologic, hormonal, you name it!
This could be a good starting point. Here are reported articles on the problem from different points of view.
http://www.thedoctorsdoctor.com/diseases/endometrial_ca.htm#pgx
For whoever follows this question, here are a few references I found after consulting a proper librarian. Those guys are gravely under-appreciated!
Zhang G, Wu L, Li B, Huang M, Zhang R, Li X. Retrospective analysis of prognostic variables and clinical outcomes in surgically staged intermediate risk endometrial carcinoma. Eur J Obstet Gynecol Reprod Biol [Internet]. Elsevier Ireland Ltd; 2013 Jul [cited 2014 Oct 12];169(2):309–16. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23540792
Fujimoto T, Nanjyo H, Fukuda J, Nakamura A, Mizunuma H, Yaegashi N, et al. Endometrioid uterine cancer: histopathological risk factors of local and distant recurrence. Gynecol Oncol [Internet]. Elsevier Inc.; 2009 Feb [cited 2014 Oct 12];112(2):342–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/19062082
Gadducci A, Cosio S, Fabrini MG, Fanucchi A, Barsotti C, Cristofani R, et al. Patterns of Failures in Endometrial Cancer : Clinicopathological Variables Predictive of the Risk of Local , Distant and Retroperitoneal Failure. Anticancer Res. 2011;3488:3483–8.
Doll KM, Tseng J, Denslow S a, Fader AN, Gehrig P a. High-grade endometrial cancer: revisiting the impact of tumor size and location on outcomes. Gynecol Oncol [Internet]. Elsevier Inc.; 2014 Jan [cited 2014 Oct 12];132(1):44–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24183734
Mariani A, Dowdy SC, Keeney GL, Long HJ, Lesnick TG, Podratz KC. High-risk endometrial cancer subgroups: candidates for target-based adjuvant therapy. Gynecol Oncol [Internet]. 2004 Oct [cited 2014 Sep 19];95(1):120–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15385120
Mariani A, Webb MJ, Keeney GL, Lesnick TG, Podratz KC. Surgical Stage I Endometrial Cancer: Predictors of Distant Failure and Death. Gynecol Oncol [Internet]. 2002 Dec [cited 2014 Oct 8];87(3):274–80. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0090825802968368
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