Piriformis syndrome (PS) is an elusive, benign medical condition. Patients usually complaint deep-seated gluteal pain with some aggravating and relieving factors. Regarding aggravating factors, prolonged sitting on the affected side, affected side lying, posture change - standing from sitting, forward bending, etc. are common, whereas walking relives pain somewhat, especially in chronic cases. In acute PS, patients have pain relieving posture finding difficulty, physicians also get confused it with more prevalent low back pain diagnosis, namely prolapsed lumbar intervertebral disc (PLID).

PS is a disorder of exclusion of clinical mimics and it has no definite cause; in literature, lumbar spinal stenosis, leg-length inequality, professional dancers, fibromyalgia, previous fall, blunt gluteal trauma, etc. are mentioned as its risk factors. Sporadic case reports and our recent systematic review addressed infective cause of piriformis muscle injury, where patients complain of clinical features unlike of PS. In piriformis muscle (PM) infection, patients report of persistent deep gluteal pain that doesn't change with posture, patients also have fever and raised laboratory inflammatory markers (raised WBC count, ESR & CRP). Moreover, there may be characteristic MRI changes in the deep-seated gluteal and pelvic structures including PM. Pain medications & PM stretching exercise don't help patient anyway, they need antimicrobials as well; when antibiotics don't work, surgical drainage of PM is required. Like in PS, intra-lesional steroid is contraindicated here. If piriformis pyomyositis is left undiagnosed and untreated precisely, life-threatening consequences may be the outcomes, hence we can consider the piriformis pyomyositis as the PM emergency.

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Suggested reading :

1. Siddiq AB, Danny Clegg, Hasan SA, Rasker JJ. Extra-spinal sciatica and sciatica mimics – a scoping review. Korean J Pain 2020; 33:305-317.

2. Siddiq AB, Rasker JJ. Piriformis pyomyositis, a cause of piriformis syndrome – A systematic search and review. Clin Rheumatol 2019; 38:1811-1821.

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