It will be difficult to find a correct answer for you for a couple of reasons. User friendliness is going to be subjective according to the user's expertise and expectations, so what fits one person's style of work may not suit you. Secondly, few workers will have in-depth knowledge of the full range of all XRD software that would equip them with sufficient experience to answer your question. This is because people tend to use whatever software is in the lab already, or what came with the diffractometer upon installation. People will tend to recommend what they know well rather than a reasoned comparison of all the choices. So for example, I am a Bruker user and have knowledge of EVA and TOPAS but in the past I have also used Siroquant, Powdercell and BGMN. I would like to consider that I have some experience in these, having worked in XRD for 27 years. However, I am inexperienced at the same time, as I have no knowledge of any Panalytical or Rigaku software (apart from when I was selecting equipment for purchase and I did compare the software then). So I can't really comment on HighScore+ or MDI-Jade.

The best you can do is to try the packages for yourself, if you can obtain trial versions - see what works best for you. It will also depend on what type of 'XRD analysis' you intend to carry out. The software chosen will vary accord to your needs: qualitative, quantitative, structural, etc.

 Thank you so much Ian J slipper and Askhan

It depends on the objective of your analysis. I use X'pert Highscore to phase identification, however TOPAS is the software I use for structural refinement. I agree with Ian, we usually prefer the software is available in the lab.