Which is the best tool to predict whether a mutation in a promoter sequence alters transcription factor binding

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Are there free online tools for the visualization of gene set (GO-) enrichment analysis results?

Gene set enrichment analyses usually end up with lists of enriched categories associated with a p-value or some othewr measure of reliability. I am looking for free visualization tools such as...

31 December 2018 9,333 1 View

What are the factors that contribute to intrinsic and acquired resistance to therapy with immune checkpoint blockers of human cancers?

Approximately 30% of cancer patients respond to ICB therapy, some for very extended periods. ICB is an enormous step forwar for many cancers such as melanoma but still, the majority of patients do...

04 May 2018 1,364 1 View

What would you consider as expression threshold for Affymetrix miRNA arrays?

Although there is no absolute threshold under which a gene must be considered as "not expressed" for Affymetrix mRNA expression arrays the vlaue of 5 (log scale) is commonly considered as...

11 December 2014 4,832 1 View

How to perform RNAseq statistics?

RNAseq delivers gene expression data from experiments with several biological replicates for two or more conditions. Once you have the processed gene expression data comparisons between conditions...

09 October 2014 6,736 10 View

Which free software for the analysis of Affymetrix aCGH/SNP array data can you recommend

I am currently using CNAG software but not entirely satisfied with it. Partek is nice but expensive. Any suggestions?

11 December 2012 8,370 3 View

any study on protective factors of care givers of dementia and resilience ?

need to review articles on care giving in dementia and challenges faced

12 August 2024 6,424 1 View

How to learn more about SPSS and its Application?

I would like to learn more about SPSS and Its application especially in regards to data analysis. Please suggest me how I can learn more about it. Thank you so much.

11 August 2024 9,101 4 View

Can I base on reverse DNA sequences to perform alignment, convert to amino acids and GenBank submission?

I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?

11 August 2024 5,138 1 View

Baseline drift in HPLC? What causes this?

Hello, Why do i see this baseline drift when i compare my blank (black) to the sample (blue)? Any suggestions as to why this happened? Thank you!

11 August 2024 3,770 4 View

Text-Communication from the M1 Hand Area using BCI—and then there is Elon Musk?

Willett, Shenoy et al. (2021) have developed a brain computer interface (BCI) that used neural signal collected from the hand area of the motor cortex (area M1) of a paralyzed patient. The...

10 August 2024 7,180 0 View

Has anyone applied Python in the field of textile engineering for data analysis, automation, or smart textiles?

I'm currently exploring the application of Python in textile engineering, specifically in areas like data analysis, process automation, and the development of smart textiles. I'm interested in...

10 August 2024 7,429 2 View

How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?

09 August 2024 7,718 0 View

How are iso-frequency contours plotted?

Let's say we have a standard, regular hexagonal honeycomb with a 3-arm primitive unit cell (something like the figure attached; the figure is only representative and not drawn to scale). The...

07 August 2024 1,937 1 View

How to prepare the nanoparticle treated fungal sample for Environmental SEM analysis?

A fungal strain was treated with nanoparticles. We want to do an environmental SEM analysis. So could anyone share your views on preparing the sample? Thank you.

07 August 2024 5,307 1 View

How to normalize and take the significance of the MTT OD values with 3 replicates for the same cell-line?

Hi, I have a question about normalizing the MTT OD values for doing the statistical analysis. So, if we have 3 different plates and we call them 3 different replicates, so, first we would...

07 August 2024 8,106 4 View