Which is the best tool to predict whether a mutation in a promoter sequence alters transcription factor binding

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Are there free online tools for the visualization of gene set (GO-) enrichment analysis results?

Gene set enrichment analyses usually end up with lists of enriched categories associated with a p-value or some othewr measure of reliability. I am looking for free visualization tools such as...

31 December 2018 9,232 1 View

What are the factors that contribute to intrinsic and acquired resistance to therapy with immune checkpoint blockers of human cancers?

Approximately 30% of cancer patients respond to ICB therapy, some for very extended periods. ICB is an enormous step forwar for many cancers such as melanoma but still, the majority of patients do...

04 May 2018 1,263 1 View

What would you consider as expression threshold for Affymetrix miRNA arrays?

Although there is no absolute threshold under which a gene must be considered as "not expressed" for Affymetrix mRNA expression arrays the vlaue of 5 (log scale) is commonly considered as...

11 December 2014 4,732 1 View

How to perform RNAseq statistics?

RNAseq delivers gene expression data from experiments with several biological replicates for two or more conditions. Once you have the processed gene expression data comparisons between conditions...

09 October 2014 6,631 10 View

Which free software for the analysis of Affymetrix aCGH/SNP array data can you recommend

I am currently using CNAG software but not entirely satisfied with it. Partek is nice but expensive. Any suggestions?

11 December 2012 8,233 3 View

How to compare two groups with only two measurements?

Hiiiii everyone! I have an enquiry on statistical analysis. I was looking for many forum and it's still cannot solve my problem. I want to compare means of two groups of data but only with two...

03 March 2021 8,796 3 View

Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence?

I am on the lookout for the Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence. Does anyone know where I can find it? Thank you in advance

03 March 2021 3,568 1 View

What kind of fluid could I use for a pitfall trap that also does not invalidate molecular testing?

Hi, I want to start testing pitfall trap to obtain ants samples, but I need to conduct molecular analysis on those insects. So, what kind of fluid can I use? Ethanol expires too early and I need...

03 March 2021 5,978 5 View

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10?

What's the best way to measure growth rates in House sparrow chicks from day 2 to day 10? Since, the growth curve from day 2 to 10 won't be like the "Logistic curve" it might not follow logistic...

03 March 2021 1,401 3 View

Do we need to write protocol for a second study of a systematic review that has been registered and published?

I have conducted and published a systematic review and meta-analysis research with the topic related to public health and health pomotion (protocol was registed in PROSPERO). Now we want to...

03 March 2021 8,920 3 View

How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

Do I need to do linear regression before running mediation analysis using PROCESS MACRO by Hayes ?

I just wanted to check if I need to run a linear regression separately if I am using PROCESS MACRO to run mediation analysis. Thank you.

02 March 2021 4,359 3 View

Sample dilution for quantitative analysis using ELISA?

If the detection range is in ng/ml but the reference range is in ug/ml for a molecule or protein in serum or plasma .how to dilute and what is the initial volume to be taken for quantitative analysis

02 March 2021 7,670 3 View

Is There Any Feasible Method To Test Fluorescent Compounds Other Than Fluorescence Spectrometers ??

Is There Any Feasible Method To Test The Efficiency Of Fluorescent Compounds Other Than UV Spectrometers ? Suggestions Would Be Appreciated !

02 March 2021 5,785 3 View

How to calculate average trend in maximum annual NDVI from MODIS?

I am wanting to calculate the average trend in maximum annual NDVI in Iceland from 2010-2020 using MODIS MYD13Q1 V6. How would I do this? I have currently inserted the NDVI bands from the MODIS...

02 March 2021 752 2 View