Whether ANN (artificial neural network) is more reliable than CCRD based optimization (Design Expert)?I have come across some papers and also during discussion in some conference, got some questions for which I am trying to find a precise solution.

Some used CCRD first for optimization of process parameters to maximize the product yield, then fed experimental result to ANN, fine tuned optimal condition.

Is that a right method?

How much reliable is ANN for optimization of process parameters?

Is it possible to use mere ANN for optimization (with actual experiments like CCRD to feed data)?

(P.N.: I have least knowledge in ANN)

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