I want to screen my compounds for telomerase inhibitor activity.
Consider a regular tetrahedron with the correlation functions for empty, point, pair, triplet and tetrahedron being u0, u1, u2, u3 and u4. Let the corresponding cluster interactions being e0, e1,...
03 May 2024 2,913 1 View
What is the critical limit of macro and micro-nutrient content in plants
16 April 2024 6,216 1 View
Does mineral and organic nitrogen fertilization modify essential oil content and chemical composition in Aromatic plants?
10 April 2024 947 0 View
I take a support for solving another equation.
21 September 2023 7,180 0 View
Rainfall pattern has been changed in 2023
17 July 2023 2,567 2 View
Discuss here
29 June 2023 9,862 3 View
I am calculating the energy of the system using quantum espresso. The input file I am using to relax Mo structure is attached to this thread. While the calculations are taking place, I...
18 April 2023 3,280 2 View
hi
11 April 2023 6,190 1 View
Numerical solution of time-fractional BBM-Burger differential equation by using Laplace transform with residual power series method. I have solved but need help to make program on mathematica...
21 March 2023 9,834 0 View
I published my research paper in Journal of Intelligent & Fuzzy Systems. This journal comes under iosPress and scopus index journal. If I search my name in the "Search for an author profile"...
22 February 2023 9,296 1 View
I am trying to measure telomere length in human DNA samples through qPCR. In the protocol, they have not included extension step. Can anybody explain how a qPCR can work without an extension step?...
31 May 2024 514 2 View
Hello, I am trying to visualize a genomic locus. I produced Alexa fluor 488 dUTP tagged FISH probes by nick translation. I used two PCR amplified DNA fragments (12kb and 16 kb) that span through...
26 January 2024 1,080 1 View
I am a bit confused about this question. I am currently attempting to do a meta-analysis on pesticide exposure and telomere length (outcome). The exposure(s) were basically presented as either a...
17 January 2024 3,267 3 View
I’m currently conducting research on telomeres in THP-1 cells. During my gel electrophoresis experiments using a 1% gel, I’ve encountered an issue where the DNA seems to be stuck at the top of the...
29 October 2023 9,561 7 View
Hello, First, let me describe the problem I'm trying to solve. I transformed yeast with an antibiotic marker to truncate a chromosome, with the fragment having a homologous sequence on one and...
05 August 2023 3,416 2 View
Hello, I have recently read about the reverse transcription activity of one of the subunits of telomerase. As far as I know, all reverse transcriptases so far are of viral origin, including the...
13 April 2023 5,870 2 View
What should be the length of telomere after treating a Particular MCF-7 cell line with a plant extract? It should decrease or increase the length of telomere? is there any particular value for...
10 March 2023 9,172 1 View
In order to assess the telomere length in human blood samples by qpcr, what is the best standard reference one can use for drawing the standard curve? I came across papers which use a pool of...
03 March 2023 2,324 7 View
(Ex: Dyskeratosis congenita)
30 January 2023 3,753 2 View
Genome Assembly result. 1 Chromosome/scaffold has false telomere joining of 2 contigs due to chromosome size of more than 90Mb. 1 chromosome: 2 telomere contigs Manually difficult to separate or...
28 November 2022 5,004 0 View